Rab 40B is a 278 amino acid protein that belongs to the small GTPase superfamily and the Rab family.
Rab 40B contains a SOCS box domain that mediates interactions with the Elongin BC complex, an adapter module in different E3 ubiquitin ligase complexes.
Rab 40B shares similarity with a yeast protein, suggesting a role in regulation of secretory vesicles.
The Rab 40B gene is conserved in chimpanzee, cow, mouse, rat, chicken and zebrafish, and maps to human chromosome 17q25.3.
It has been suggested that there is a major gene locus on chromosome 17q25.3 for autosomal dominant moyamoya disease (MMD), which is an idiopathic steno-occlusive cerebrovascular disease that represents an important cause of stroke.
Applications:Suitable for use in Western Blot.
Other applications not tested.
Recommended Dilution:Western Blot: 1:500-1:1000Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：100ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid PBS, 0.1% sodium azide, 50% glycerol.
Specificity：Recognizes endogenous levels of Rab 40B. Species Crossreactivity: Human, mouse, rat
Isotype：IgG
Calc Applications Abbrev：WB
Calc Crossreactivity：Hu Mo Rt
Immunogen：Synthetic peptide corresponding to amino acids 250-300 of Human Rab 40B.
