PRUNE2 (prune homolog 2 (Drosophila)), also known as BMCC1 (BNIP2 motif-containing molecule at the C-terminal region 1) or BNIPXL, is a 3,088 amino acid cytoplasmic protein that belongs to the PPase class C family and PRUNE subfamily.
PRUNE2 is involved in the survival and aggressiveness of tumor cells and may also play a role in differentiation.
Highly expressed in the nervous system and adrenal gland, PRUNE2 exists as five alternatively spliced isoforms and is induced during the G1 phase of the cell cycle.
PRUNE2 contains one CRAL-TRIO domain and is encoded by a gene that maps to human chromosome 9q21.13.
Chromosome 9 houses over 900 genes and comprises nearly 4% of the human genome.
Hereditary hemorrhagic telangiectasia, which is characterized by harmful vascular defects, and Familial dysautonomia, are both associated with chromosome 9.
Notably, chromosome 9 encompasses the largest interferon family gene cluster.
Applications:Suitable for use in Western Blot, Immunohistochemistry.
Other applications not tested.
Recommended Dilution:Western Blot: 1:500-1:2000Immunohistochemistry: 1:50-1:200Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：50ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid PBS, 0.1% sodium azide, 50% glycerol.
Specificity：Recognizes endogenous levels of PRUNE2. Species Crossreactivity: Human
