84-2384-77　［取扱停止］PROC (Activation peptide, Anticoagulant Protein C, APC, Autoprothrombin IIA, Blood coagulation Factor XIV, EC 3.4.21.69, PC, proC, PROC, PROC1, Protein C (inactivator of coagulation Factors Va and VIIIa), THPH3, THPH4, Vitamin K Dependent Protein C, Vitamin K Dependent Protein C Precursor) 50ul　225259

特徴

• Protein C is a vitamin K-dependent plasma protein that is produced in the liver and made up of two polypeptide chains.
• It is an important anti-coagulant activated by Thrombin bound to an endothelial surface receptor and it enzymatically cleaves activated forms of Factors V and VIII, thus inhibiting blood coagulation.
• Protein C is similar to the prothrombin group of blood coagulation factors in its primary structure.
• Normal protein C concentration in human plasma is ~1-3 ng/ml and the proenzyme concentration is ~3 µg/ml.
• Protein C deficiency is associated with inherited thrombophilia, a rare genetic disorder that predisposes affected individuals to venous thrombosis and habitual abortion.
• Applications:Suitable for use in Western Blot, Immunohistochemistry.
• Other applications not tested.
• Recommended Dilution:Western Blot: 1:500-1:2000Immunohistochemistry: 1:50-1:200Optimal dilutions to be determined by the researcher.
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months after receipt.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.