84-2383-99　［取扱停止］PPP2R4 (Subunit B'', KIAA0044, MGC2184, Phosphotyrosyl Phosphatase Activator, PP2A, PP2A Phosphatase Activator, PP2A Subunit B', PP2A Subunit B' Isoform PR53, PP2A Subunit B' PR53 Isoform, PPP2R4, PR53, PR53 Isoform, Protein Phosphatase 2, Regulatory Subunit B-prime, Protein Phosphatase 2A Activator Regulatory Subunit 4, Protein Phosphatase 2A Regulatory Subunit B ...　225216

特徴

• Protein phosphatase 2A is one of the four major Ser/Thr phosphatases and is implicated in the negative control of cell growth and division.
• Protein phosphatase 2A holoenzymes are heterotrimeric proteins composed of a structural subunit A, a catalytic subunit C, and a regulatory subunit B.
• The regulatory subunit is encoded by a diverse set of genes that have been grouped into the B/PR55, B'/PR61, and B''/PR72 families.
• These different regulatory subunits confer distinct enzymatic specificities and intracellular localizations to the holozenzyme.
• The product of this gene belongs to the B' family.
• This gene encodes a specific phosphotyrosyl phosphatase activator of the dimeric form of protein phosphatase 2A.
• Alternative splicing results in multiple transcript variants encoding different isoforms.
• Applications:Suitable for use in Western Blot, Immunohistochemistry.
• Other applications not tested.
• Recommended Dilution:Western Blot: 1:500-1:2000Immunohistochemistry: 1:50-1:200Optimal dilutions to be determined by the researcher.
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months after receipt.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.