PPP1R19, also known as RMP (RPB5-mediating protein), C19orf2, NNX3 or URI, is a 534 amino acid protein that localizes to the nucleus and belongs to the RNA polymerase II subunit 5-mediating protein family.
Expressed ubiquitously, RMP functions as a component of the multi-protein URI complex and is thought to play a role in protein scaffolding that may be involved in transcription and ubiquitination.
Multiple isoforms of RMP exist due to alternative splicing events.
The gene encoding RMP maps to human chromosome 19, which consists of over 63 million bases, houses ~1,400 genes and is recognized for having the greatest gene density of the human chromosomes.
Applications:Suitable for use in Western Blo and, Immunohistochemistry.
Other applications not tested.
Recommended Dilutions:Western Blot: 1:500-1:1000Immunohistochemistry: 1:50-1:200Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：100ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid PBS, pH 7.2, 0.05% sodium azide
Specificity：Recognizes endogenous levels of human PPP1R19. Species Crossreactivity: mouse and rat
Isotype：IgG
Calc Applications Abbrev：IHC WB
Calc Crossreactivity：Hu Mo Rt
Immunogen：Synthetic peptide corresponding to aa181-226 of human PP1R19
