84-2383-22　［取扱停止］POLR2K (DNA-directed RNA Polymerases I, II, and III Subunit RPABC4, RNA Polymerases I, II, and III Subunit ABC4, ABC10-alpha, DNA-directed RNA Polymerase II Subunit K, RNA Polymerase II 7.0kD Subunit, RPB7.0, RPB10alpha, POLR2K) 50ul　225174

特徴

• RNA polymerase II (Pol II) is a multi-subunit enzyme responsible for the transcription of protein-coding genes.
• Transcription initiation requires recruitment of the complete transcription machinery to a promoter via solicitation by activators and chromatin remodeling factors.
• Pol II can coordinate 10 to 14 subunits.
• This complex interacts with the promoter regions of genes and a variety of elements and transcription factors.
• POLR2K (polymerase (RNA) II (DNA directed) polypeptide K), also known as RPB12, RPABC4, RPB7.0, hRPB7.0, hsRPB10a, RPB10alpha or ABC10-alpha, is a 58 amino acid nuclear protein belonging to the archaeal rpoP/eukaryotic RPC10 RNA polymerase subunit family.
• The gene encoding POLR2K is located on human chromosome 8, which consists of nearly 146 million base pairs, houses more than 800 genes and is associated with a variety of diseases and malignancies.
• Applications:Suitable for use in Western Blot.
• Other applications not tested.
• Recommended Dilution:Western Blot: 1:500-1:1000Optimal dilutions to be determined by the researcher.
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months after receipt.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.