84-2383-01　［取扱停止］POLR1C (DNA-directed RNA Polymerases I and III Subunit RPAC1, DNA-directed RNA Polymerase I Subunit C, RNA Polymerases I and III, Subunit AC1, AC40, DNA-directed RNA Polymerases I and III 40kD Polypeptide, RPA40, RPA39, RPC40, POLR1C, POLR1E) 100ul　225163

特徴

• RNA polymerases transcribe nuclear genes for ribosomal RNA, thus representing ribosomal biogenesis.
• RNA polymerase I (Pol I) is located in the nucleolus and transcribes class I genes, which code for large ribosomal RNA.
• Different subunits of the Pol I transcription machinery are targets of various physiological stimuli, which suggests that multiple signaling pathways are involved in carrying out Pol I transcription.
• RPA16, RPA40 and RPA135 are subunits of Pol I that associate with each other at an early stage of RNA Pol I assembly.
• RPA40 is essential for the function and integrity of the complex and is also an essential subunit of RNA polymerase III (Pol III).
• Applications:Suitable for use in Western Blot, Immunohistochemistry.
• Other applications not tested.
• Recommended Dilution:Western Blot: 1:500-1:2000Immunohistochemistry: 1:50-1:200Optimal dilutions to be determined by the researcher.
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months after receipt.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.