84-2382-95　［取扱停止］POLR1A (DNA-directed RNA Polymerase I Subunit RPA1, RNA Polymerase I Subunit A1, A190, DNA-directed RNA Polymerase I largest Subunit, DNA-directed RNA Polymerase I Subunit A, RNA Polymerase I 194kD Subunit, RPA194, POLR1A) 50ul　225161

特徴

• RNA polymerases transcribe nuclear genes for ribosomal RNA, thus representing ribosomal biogenesis.
• RNA polymerase I (Pol I) is located in the nucleolus and transcribes class I genes, which code for large ribosomal RNA.
• Different subunits of the Pol I transcription machinery are targets of various physiological stimuli, which suggests that multiple signaling pathways are involved in carrying out Pol I transcription.
• RPA40 and RPA16 are subunits of Pol I that associate with each other at an early stage of RNA polymerase I assembly.
• RPA40 is essential for the function and integrity of the complex and is also an essential subunit of RNA polymerase III (Pol III).
• RPA40, RPA16 and RPA135 encode the three subunits of RNA polymerase I, respectively.
• RPA194 is the largest subunit of RNA Pol I and is not a component of Pol II and Pol III.
• Applications:Suitable for use in Western Blot.
• Other applications not tested.
• Recommended Dilution:Western Blot: 1:500-1:1000Optimal dilutions to be determined by the researcher.
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months after receipt.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.