Gross cystic disease fluid protein 15 (GCDFP-15) is a major protein component of benign breast gross cysts.
It is a known marker of breast cancer, as it is found in ~50% of all breast cancer specimens.
GCDFP-15, also known as PIP, for prolactin inducible protein, is a prolactin and androgen controlled protein.
It is detectable in saliva, tears, sweat, seminal plasma, submucosal glands of the lung and amniotic fluid.
PIP, the gene encoding GCDFP-15 is expressed in exocrine glands and, in pathologic conditions, in breast cysts and breast cancers exhibiting apocrine features.
The PIP gene maps to the long arm of chromosome 7, a region frequently altered in mammary tumors.
Applications:Suitable for use in Western Blot, Immunohistochemistry.
Other applications not tested.
Recommended Dilution:Western Blot: 1:500-1:2000Immunohistochemistry: 1:50-1:200Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：50ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid PBS, 0.1% sodium azide, 50% glycerol.
Specificity：Recognizes endogenous levels of PIP. Species Crossreactivity: Human
