Peroxins are proteins involved in peroxisome biogenesis The peroxisome biogenesis factor Peroxin 2 (also designated Pex2) is an integral membrane protein of peroxisomes.
Defects in the PXMP3 gene encoding Peroxin 2 are the cause of Zellweger syndrome-1 (ZWS-1), an autosomal recessive disorder due to defective import mechanisms for peroxisomal matrix enzymes.
ZWS-1 is a severe form of the peroxisome-biogenesis disorders, a group of genetically heterogeneous, lethal diseases that are characterized by neuronal, hepatic and renal abnormalities, mental retardation and, in their most severe form, death within the first year of life.
Applications:Suitable for use in Western Blot, Immunohistochemistry.
Other applications not tested.
Recommended Dilution:Western Blot: 1:500-1:1000Immunohistochemistry: 1:50-1:200Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size:50ul
Host:rabbit
Source Antibody:human
Grade:Affinity Purified
Purity:Purified by immunoaffinity chromatography.
Form:Supplied as a liquid PBS, 0.05% sodium azide, pH 7.2.
Specificity:Recognizes endogenous levels of Peroxin 2. Species Crossreactivity: Human
Isotype:IgG
Calc Applications Abbrev:IHC WB
Calc Crossreactivity:Hu
Immunogen:Synthetic peptide corresponding to the N-terminal of Human Peroxin 2.