A farnesylated protein, Peroxin 19 (peroxisomal farnesylated protein, PxF or HK33), localizes to the outer surface of peroxisomes.
Specifically, Peroxin 19 localizes to the cytoplasmic surface of peroxisomes in liver cells.
Peroxin 19 is the human homolog of Pex19p, an oleic acid-inducible, farnesylated protein that is essential for peroxisome biogenesis in Saccharomyces cerevisiae.
The carboxy-terminal part of Peroxin 19, including the CAAX homology box, is required for its biologic function.
Moreover, Peroxin 19 is apparently involved in the initial stage of peroxisome membrane assembly, before the import of matrix protein.
Applications:Suitable for use in Western Blot, Immunohistochemistry.
Other applications not tested.
Recommended Dilution:Western Blot: 1:500-1:2000Immunohistochemistry: 1:50-1:200Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：50ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid PBS, 0.1% sodium azide, 50% glycerol.
Specificity：Recognizes endogenous levels of Peroxin 19. Species Crossreactivity: Human, mouse, rat
Isotype：IgG
Calc Applications Abbrev：IHC WB
Calc Crossreactivity：Hu Mo Rt
Immunogen：Recombinant full length Human Peroxin 19.
