The Peroxin gene family, which includes more than 20 members, is required for peroxisome biogenesis.
Peroxin 10 (Peroxisome biogenesis factor 10), also known as RNF69 (RING finger protein 69), is a 326 amino acid protein that exhibits E3 ligase activity in vitro, suggesting that it is involved in Ubc4-dependent ubiquination.
Defects in the gene encoding Peroxin 10 are the result of a number of different disorders, such as Peroxisome biogenesis disorder complementation group 7, Zellweger syndrome and adrenoleukodystrophy neonatal.
There are two isoforms of Peroxin 10 that are produced as a result of alternative splicing events.
Applications:Suitable for use in Western Blot, Immunohistochemistry.
Other applications not tested.
Recommended Dilution:Western Blot: 1:500-1:1000Immunohistochemistry: 1:50-1:200Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：50ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid PBS, 0.05% sodium azide, pH 7.2.
Specificity：Recognizes endogenous levels of Peroxin 10. Species Crossreactivity: Human
Isotype：IgG
Calc Applications Abbrev：IHC WB
Calc Crossreactivity：Hu
Immunogen：Synthetic peptide corresponding to amino acids 191-240 of Human Peroxin 10.
