This gene is a member of the PAR6 family and encodes a protein with a PSD95/Discs-large/ZO1 (PDZ) domain and a semi-Cdc42/Rac interactive binding (CRIB) domain.
This cell membrane protein is involved in asymmetrical cell division and cell polarization processes as a member of a multi-protein complex.
The protein also has a role in the epithelial-to-mesenchymal transition (EMT) that characterizes the invasive phenotype associated with metastatic carcinomas.
Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Applications:Suitable for use in Western Blot, Immunohistochemistry.
Other applications not tested.
Recommended Dilution:Western Blot: 1:500-1:2000Immunohistochemistry: 1:50-1:200Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：100ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid PBS, 0.1% sodium azide, 50% glycerol.
Specificity：Recognizes endogenous levels of PARD6A. Species Crossreactivity: Human
Isotype：IgG
Calc Applications Abbrev：IHC WB
Calc Crossreactivity：Hu
Immunogen：Recombinant full length Human PARD6A.
Shelf Life：1year
Swiss Prot Number：Q9NPB6
EU Commodity Code：30021010
商品名：PARD6A (Par 6 partitioning defective 6 C elegans Homolog alpha, Par 6 partitioning defective 6 Homolog alpha, Par 6 partitioning defective 6 Homolog alpha C elegans, PAR 6A, PAR-6 alpha, PAR-6, par-6 Family Cell polarity Regulator alpha, PAR-6A, PAR6, PAR6A_HUMAN, PAR6alpha, PAR6C, Pard6a, Partitioning defective 6 Homolog alpha, partitioning-defective Protein 6, partitioning-defective Protein 6, C. elegans, Homolog of, alpha, Tax interacting Protein 40, Tax interaction Protein 40, TAX40, TIP 40, TIP-40, TIP40,) 100ul
