Glycodelin (also designated GD, placental protein 14, PP14, progesterone-associated endometrial protein, progestagen-associated endometrial protein, pregnancy-associated endometrial alpha-2 globulin, PAEG or PEG) is a glycoprotein with structural homology to beta-lactoglobulins.
Glycodelin is synthesized by the secretory endometrium and decidua during embryo implantation and in the first few weeks of pregnancy.
It is expressed in steroid responsive tissues of the female reproductive tract and in the paranucleolar vacuole, which is characteristically present in lobular breast cancer cells.
Glycodelin expression in breast cancer cells is accompanied by the acquisition of a phenotype of organized glandular epithelium.
Applications:Suitable for use in Western Blot, Immunohistochemistry.
Other applications not tested.
Recommended Dilution:Western Blot: 1:500-1:2000Immunohistochemistry: 1:50-1:200Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size:50ul
Host:rabbit
Source Antibody:human
Grade:Affinity Purified
Purity:Purified by immunoaffinity chromatography.
Form:Supplied as a liquid PBS, 0.1% sodium azide, 50% glycerol.
Specificity:Recognizes endogenous levels of PAEP. Species Crossreactivity: Human