84-2376-06　［取扱停止］p68 RNA (ATP Dependent RNA Helicase DDX5, DDX 5, Ddx5, DDX5, DEAD (Asp Glu Ala Asp) box Helicase 5, DEAD (Asp Glu Ala Asp) box Polypeptide 5, DEAD box 5, DEAD box Protein 5, DEAD/H (Asp Glu Ala Asp/His) box Polypeptide 5 (RNA Helicase, 68kD), DEAD/H (Asp Glu Ala Asp/His) box Polypeptide 5, DEAD/H (Asp-Glu-Ala-Asp/His) box Polypeptide 5 (RNA Helicase 68kDa), DEAD/H ...　224814

特徴

• p68 RNA Helicase is a nuclear protein that exhibits RNA-dependent ATPase activity.
• Phosphorylation by protein kinase C inhibits p68 RNA Helicase activity.
• p68 RNA Helicase appears to play a role in organ differentiation during development.
• Furthermore, p68 RNA Helicase is expressed in early neural development and in various mesodermal tissues in a number of different chordate embryos.
• At the cellular level, the expression levels of p68 RNA Helicase increase in serum-induced quiescent cell lines.
• p68 RNA Helicase may function as a coactivator for estrogen receptor alpha.
• Additionally, p68 RNA Helicase associates with transcriptional coactivators CBP and p300.
• p68 RNA Helicase localizes to the nucleus under normal conditions.
• During late telophase, p68 RNA Helicase and fibrillarin colocalize to nascent nucleoli.
• p68 RNA Helicase may function as a heterodimer with p72 RNA Helicase.
• Applications:Suitable for use in Western Blot.
• Other applications not tested.
• Recommended Dilution:Western Blot: 1:500-1:1000Optimal dilutions to be determined by the researcher.
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months after receipt.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.