OXA1L (oxidase (cytochrome c) assembly 1-like), also known as OXA1, is a 435 mitochondrial inner membrane protein belonging to the evolutionarily conserved Oxa1/Alb3/yidC protein family.
Members of the Oxa1/Alb3/yidC protein family are involved in the biogenesis of membrane proteins in mitochondria, chloroplasts and bacteria.
Existing as three isoforms produced by alternative splicing events, OXA1L is required for the insertion of integral membrane proteins into the mitochondrial inner membrane.
OXA1L is essential for the activity and assembly of cytochrome oxidase and for the correct biogenesis of F(1)F(o)-ATP synthase and NADH:ubiquinone oxidoreductase.
Mutations in the gene encoding OXA1L might be involved in the pathology of combined enzymatic deficiencies of the oxidative phosphorylation (OXPHOS) system.
Applications:Suitable for use in Western Blot, Immunohistochemistry and Immunofluorescence.
Other applications not tested.
Recommended Dilution:Western Blot: 1:500-1:2000Immunohistochemistry: 1:50-1:200Immunofluorescence: 1:10-1:100Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：50ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid PBS, pH 7.2, 0.02% sodium azide, 50% glycerol.
Specificity：Recognizes endogenous levels of human OXA1L. Species Crossreactivity: mouse and rat
Isotype：IgG
Calc Applications Abbrev：IF IHC WB
Calc Crossreactivity：Hu Mo Rt
Immunogen：Recombinant protein corresponding to full length human OXA1L.
