84-2372-91　［取扱停止］NUB1 (NEDD8 ultimate buster 1, Negative Regulator of Ubiquitin-like Proteins 1, Renal Carcinoma Antigen NY-REN-18, NUB1, NYREN18) 50ul　224656

特徴

• NEDD8 is a ubiquitin-like protein that controls vital biological events through its conjugation to cullin proteins.
• NEDD8 ultimate buster-1 (NUB1), is a negative regulator of the NEDD8 system that recruits NEDD8 and its conjugates to the proteasome for degradation.
• It is, therefore a cell growth regulator.
• The UBA domain of NUB1 is the specific acceptor for the linear ubiquitin precursor.
• NUB1 is composed of 601 amino acids.
• It is an interferon-inducible protein and predominantly localizes in the nucleus.
• NUB1 is specifically expressed in adult human testis, ovary, heart, and skeletal muscle tissues.
• Applications:Suitable for use in Western Blot, Immunohistochemistry.
• Other applications not tested.
• Recommended Dilution:Western Blot: 1:500-1:1000Immunohistochemistry: 1:50-1:200Optimal dilutions to be determined by the researcher.
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months after receipt.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.