84-2372-55 [取扱停止]NRF3 (Nrf3, NFE2L3, Nuclear Factor erythroid 2-Related Factor 3) 50ul 224638
特徴
- Nrf3 (nuclear factor (erythroid-derived 2)-like 3, NFE2L3, NF-E2-related factor 3, NRF3) is a transcription factor that influences placental gene expression and development.
- Nrf3 contains a Cap'n'collar (CNC)-type basic leucine zipper (bZIP) domain, and belongs to the CNC gene family.
- CNC genes play important roles in development, differentiation, oncogenesis, and stress signaling.
- Nrf3 protein is detectable in primary placental cytotrophoblasts.
- The human choriocarcinoma cell lines BeWo and JAR from trophoblastic tumors of the placenta express Nrf3 transcripts.
- Nrf3/MAFG heterodimers recognize nuclear factor-erythroid 2/Maf recognition element-type DNA-binding motifs.
- Keratinocyte growth factor (KGF)-regulates Nrf3-dependent gene expression during cutaneous wound repair.
- Applications:Suitable for use in Western Blot.
- Other applications not tested.
- Recommended Dilution:Western Blot: 1:500-1:1000Optimal dilutions to be determined by the researcher.
- Storage and Stability:May be stored at 4°C for short-term only.
- Aliquot to avoid repeated freezing and thawing.
- Store at -20°C.
- Aliquots are stable for 12 months after receipt.
- For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
- Size:50ul
- Host:rabbit
- Source Antibody:human
- Grade:Affinity Purified
- Purity:Purified by immunoaffinity chromatography.
- Form:Supplied as a liquid PBS, 0.05% sodium azide, pH 7.2.
- Specificity:Recognizes endogenous levels of Human Nrf3.
- Isotype:IgG
- Calc Applications Abbrev:WB
- Calc Crossreactivity:Hu
- Immunogen:Synthetic peptide corresponding to amino acids 500-520 of Human Nrf3.
- Shelf Life:1year
- Swiss Prot Number:Q9Y4A8
- EU Commodity Code:30021010
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