This gene is a member of the nuclear factor of activated T cells (NFAT) family.
The product of this gene is a DNA-binding protein with a REL-homology region (RHR) and an NFAT-homology region (NHR).
This protein is present in the cytosol and only translocates to the nucleus upon T cell receptor (TCR) stimulation, where it becomes a member of the nuclear factors of activated T cells transcription complex.
This complex plays a central role in inducing gene transcription during the immune response.
Alternate transcriptional splice variants encoding different isoforms have been characterized.
Applications:Suitable for use in Western Blot.
Other applications not tested.
Recommended Dilution:Western Blot: 1:500-1:2000Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size:50ul
Host:rabbit
Source Antibody:human
Grade:Affinity Purified
Purity:Purified by immunoaffinity chromatography.
Form:Supplied as a liquid PBS, 0.1% sodium azide, 50% glycerol.
Specificity:Recognizes endogenous levels of NFATC2. Species Crossreactivity: Human, mouse, rat
Isotype:IgG
Calc Applications Abbrev:WB
Calc Crossreactivity:Hu Mo Rt
Immunogen:Recombinant full length Human NFATC2.
Shelf Life:1year
Swiss Prot Number:Q13469
EU Commodity Code:30021010
商品名:NFATC2 (Cytoplasmic 2, KIAA0611, NF ATp, NF-ATc2, NF-ATp, NFAC2_HUMAN, NFAT 1, NFAT pre existing Subunit, NFAT pre-existing Subunit, NFAT Transcription Complex, preexisting Component, NFAT1, NFAT1-D, NFATc2, NFATp, Nuclear Factor of Activated T Cells Cytoplasmic 2, Nuclear Factor of Activated T Cells Cytoplasmic calcineurin Dependent 2, Nuclear Factor of Activated T Cells pre-existing Component, Nuclear Factor of Activated T-Cells, T Cell Transcription Factor NFAT 1, T-Cell Transcription Factor NFAT1,) 50ul