Members of the Neurexophilin family are neuropeptide-like glycoproteins that undergo proteolytic processing after synthesis.
As secreted proteins, Neurexophilins are thought to function as signaling molecules which specifically bind to target proteins, such as neurexin Iå (a protein that promotes adhesion between dendrites and axons), and are essential for proper neurotransmitter release.
Neurexophilins contain five common domains including a variable N-terminal domain, a highly conserved N-glycosylated central domain, a short linker region and a cysteine-rich conserved C-terminal domain.
Neurexophilin-4, also known as NXPH4 or NPH4, is a 308 amino acid secreted protein belonging to the neurexophilin family.
Neurexophilin-4 is expressed in brain, spleen and testis.
Applications:Suitable for use in Western Blot, Immunohistochemistry.
Other applications not tested.
Recommended Dilution:Western Blot: 1:500-1:1000Immunohistochemistry: 1:50-1:200Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：100ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid PBS, 0.05% sodium azide, pH 7.2.
Specificity：Recognizes endogenous levels of Neurexophilin-4. Species Crossreactivity: Human, mouse, rat
Isotype：IgG
Calc Applications Abbrev：IHC WB
Calc Crossreactivity：Hu Mo Rt
Immunogen：Synthetic peptide corresponding to amino acids 221-270 of Human Neurexophilin-4.
