84-2368-79　［取扱停止］Nek9 (DKFZp434D0935, KIAA1995, MGC138306, MGC16714, NEK 9, Nek8, nek9, NEK9, Nercc 1 Kinase, NERCC, NERCC1, Nercc1 Kinase, Never in mitosis A Related Kinase 9, Never in mitosis A-Related Kinase 9, NIMA (never in mitosis Gene a) Related Kinase 9, NIMA Related Kinase 8, NIMA Related Kinase 9, NIMA Related Kinase Nek8, NimA Related Protein Kinase 9, NIMA-Related Kina ...　224449

特徴

• Nek9 [NIMA (never in mitosis gene a)- related kinase 9], also known as serine/threonine-protein kinase Nek9, NERCC, NERCC1, MGC16714, MGC138306 or DKFZp434D0935, is a 979 amino acid protein that localizes to cytoplasm and nucleus.
• Highly expressed in liver, heart, kidney and testis, Nek9 is also expressed at lower levels in fibroblasts and smooth muscle cells.
• Nek9 regulates G1/S transition and S phase progression by influencing spindle dynamics and chromosome separation.
• Nek9 phosphorylates different histones (Histone H3 on serine and threonine), myelin basic protein, beta-casein (serine) and BICD2.
• Nek9 interacts with Ran GTPase, Nek6, Nek7, BICD2, SSRP1 and SUPT16H/FACT complex.
• Applications:Suitable for use in Immunofluorescence, Western Blot.
• Other applications not tested.
• Recommended Dilution:Western Blot: 1:500-1:1000Immunofluorescence: 1:50-1:200Optimal dilutions to be determined by the researcher.
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months after receipt.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.