Neuron navigator 3 (NAV3), also known as pore membrane and/or filamentinteracting-like protein 1 (POMFIL1), unc-53 homolog 3 (unc53H3) or STEERIN3, is a 2,385 amino acid protein that localizes to the nuclear outer membrane and plays a role in neuron regeneration.
Existing as three alternatively spliced isoforms, Neuron navigator 3 is highly expressed in adult and fetal brain and is found at moderate to low levels in ovary, lung, testis, placenta and heart.
Neuron navigator 3 is thought be involved in the regulation of IL-2 production and contains one CH (calponin-homology) domain, three N-terminal hydrophobic domains, multiple N-glycosylation sites, three ATP/GTP-binding A motifs (P loops) and several phosphorylation sites.
Applications:Suitable for use in Western Blot.
Other applications not tested.
Recommended Dilution:Western Blot: 1:500-1:1000Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：50ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid PBS, 0.1% sodium azide, 50% glycerol.
Specificity：Recognizes endogenous levels of NAV3. Species Crossreactivity: Human, mouse, rat
Isotype：IgG
Calc Applications Abbrev：WB
Calc Crossreactivity：Hu Mo Rt
Immunogen：A synthetic peptide corresponding to residues in Human NAV3.
