Myosins are highly conserved, ubiquitously expressed proteins that interact with actin to generate the force for cellular movements.
The human genome encodes over 40 different Myosin genes which are divided into distinct classes, the most notable of which are the conventional Myosins (class II) and the unconventional Myosins (classes I and III through XVIII).
Myosin IIIb (MYO3B) is a 1,341 amino acid cytoplasmic and cytoskeletal protein that is though to have an actin-based motor and possesses protein kinase activity.
Expressed in testis, retina and kidney, Myosin IIIb exists as seven alternatively spliced isoforms that belong to the STE Ser/Thr protein kinase family and protein kinase superfamily.
Myosin IIIb contains one Myosin head-like domain, a protein kinase domain and two IQ domains.
Applications:Suitable for use in Western Blot.
Other applications not tested.
Recommended Dilution:Western Blot: 1:500-1:1000Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size:50ul
Host:rabbit
Source Antibody:human
Grade:Affinity Purified
Purity:Purified by immunoaffinity chromatography.
Form:Supplied as a liquid PBS, 0.05% sodium azide, pH 7.2.
Specificity:Recognizes endogenous levels of Myosin IIIb. Species Crossreactivity: Human, mouse, rat
Isotype:IgG
Calc Applications Abbrev:WB
Calc Crossreactivity:Hu Mo Rt
Immunogen:A synthetic peptide corresponding to residues in Human Myosin IIIb.