84-2367-05　［取扱停止］MYH9 (Myosin-9, Cellular Myosin Heavy Chain, Type A, Myosin Heavy Chain 9, Myosin Heavy Chain, non-muscle Iia, Non-muscle Myosin Heavy Chain A, NMMHC-A, Non-muscle Myosin Heavy Chain Iia, NMMHC II-a, NMMHC-IIA, MYH9) 100ul　224362

特徴

• Actin is a highly conserved protein that is expressed in all eukaryotic cells.
• Actin filaments can form both stable and labile structures and are crucial components of microvilli and the contractile apparatus of muscle cells.
• Myosin is a hexamer of 2 heavy chains (MHC) and 4 light chains (MLC) that interacts with actin to generate the force for diverse cellular movements, including cytokinesis, phagocytosis and muscle contraction.
• Myosin heavy chain 9 can also be designated Myosin IIa, nonmuscle myosin heavy chain IIa, Cellular myosin heavy chain, type A, myosin-9 or NMMHC-IIA.
• Myosin heavy chain 9 is involved in cell shape, cytokinesis, and specialized functions such as capping and secretion.
• It is expressed in leukoctyes and in kidney glomeruli.
• Defects in the MYH9 gene, which encodes myosin heavy chain 9, are linked to Sebastian syndrome (SBS), Fechtner syndrome (FTNS), Alport syndrome with macrothrombocytopenia (APSM), autosomal dominant nonsyndromic sensorineural deafness 17 (DFNA17) and Epstein syndrome (EPS).
• Applications:Suitable for use in Western Blot.
• Other applications not tested.
• Recommended Dilution:Western Blot: 1:500-1:1000Optimal dilutions to be determined by the researcher.
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months after receipt.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.