Mina53, also known as MINA (MYC induced nuclear antigen), MDIG or NO52, is a 465 amino acid protein that contains one JmjC domain and localizes to the nucleus.
Expressed in placenta, liver, heart, pancreas and skeletal muscle, Mina53 is thought to be involved in ribosome biogenesis, specifically in the assembly of pre-ribosomal particles.
Via its involvement in ribosome biogenesis, Mina53 may play an important role in cell growth and survival, as well as overall cellular proliferation events.
Mina53 expression is upregulated in esophageal squamous cell carcinoma (ESCC), colon cancer and lung cancer tissues, suggesting that Mina53 may be involved in tumorigenesis.
Multiple isoforms of Mina53 exist due to alternative splicing events.
Applications:Suitable for use in Western Blot.
Other applications not tested.
Recommended Dilution:Western Blot: 1:500-1:1000Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：100ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid PBS, 0.05% sodium azide, pH 7.2.
Specificity：Recognizes endogenous levels of MINA. Species Crossreactivity: Human, mouse, rat
Isotype：IgG
Calc Applications Abbrev：WB
Calc Crossreactivity：Hu Mo Rt
Immunogen：A synthetic peptide corresponding to residues in Human MINA.
