Monoacylglycerol O-acyltransferase (MGAT) catalyzes diacylglycerol (a precursor to triacylglycerol) synthesis.
MGAT is important in intestinal absorption of dietary fat because resynthesis of triacylglycerol is needed for the assembly of the lipoproteins that transport absorbed fat to tissues.
MGAT1 is expressed in stomach, kidney, liver and adipose tissue but is not found in the intestine.
On the contrary, MGAT2 (monoacylglycerol O-acyltransferase 2) is highly expressed in the small intestine as well as in kidney, liver, colon, stomach and white adipose tissue.
MGAT 3 (monoacylglycerol O-acyltransferase 3) is highly homologous to MGAT1 and MGAT2.
The expression of MGAT3 is restricted to the gastrointestinal tract, most concentrated in the ileum.
Applications:Suitable for use in Western Blot, Immunohistochemistry.
Other applications not tested.
Recommended Dilution:Western Blot: 1:500-1:2000Immunohistochemistry: 1:50-1:200Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：100ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid PBS, 0.1% sodium azide, 50% glycerol.
Specificity：Recognizes endogenous levels of MGAT1. Species Crossreactivity: Human
