Mitogen Activated Protein Kinase Kinase 7 (MEK 7 or MKK 7) is a 38kDa member of a tyrosine/threonine protein kinase family that activates the c Jun NH2-terminal kinases (JNK), which is part of the inflammation/stress signaling pathway.
Phosphorylation of MEK 7 by MEKK 1 on serine 271 and threonine 275 in the catalytic domain activates the protein and enables MEK 7 to phosphorylate JNK.
Applications:Suitable for use in Western Blot.
Other applications not tested.
Recommended Dilution:Western Blot: 1:500-1:1000Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：50ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid PBS, 0.05% sodium azide, pH 7.2.
Specificity：Recognizes endogenous levels of MEK-7. Species Crossreactivity: Human, mouse, rat
Isotype：IgG
Calc Applications Abbrev：WB
Calc Crossreactivity：Hu Mo Rt
Immunogen：Synthetic peptide corresponding to amino acids 241-290 of Human MEK-7.
