MDH2 (malate dehydrogenase, NAD mitochondrial), also known as MDH, MOR1 or M-MDH, is a 338 amino acid that belongs to the LDH/MDH superfamily.
MDH2 localizes to the mitochondria and may play a critical role in the malate-aspartate shuttle that operates in the metabolic coordination between cytosol and mitochondria.
MDH2 utilizes the NAD/NADH cofactor system in the citric acid cycle to catalyze the reversible oxidation of malate to oxaloacetate.
Oxaloacetate is involved in many important metabolic pathways including amino acid synthesis, gluconeogenesis and facilitation of the exchange of metabolites between cytoplasm and subcellular organelles.
Applications:Suitable for use in Western Blot, Immunohistochemistry.
Other applications not tested.
Recommended Dilution:Western Blot: 1:500-1:2000Immunohistochemistry: 1:50-1:200Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：100ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid PBS, 0.1% sodium azide, 50% glycerol.
Specificity：Recognizes endogenous levels of MDH2. Species Crossreactivity: Human, mouse, rat
