84-2361-10 [取扱停止]MCM3 (Cervical Cancer proto Oncogene 5, DNA Polymerase alpha holoenzyme Associated P1, DNA Polymerase alpha holoenzyme Associated Protein P1, DNA Polymerase alpha holoenzyme-Associated Protein P1, DNA replication Factor MCM3, DNA Replication Licensing Factor MCM3, HCC 5, HCC5, hRlf beta Subunit, Human cervical Cancer proto Oncogene 5, MCM 3, mcm3, MCM3 minichromos ... 224059
84-2361-10 [取扱停止]MCM3 (Cervical Cancer proto Oncogene 5, DNA Polymerase alpha holoenzyme Associated P1, DNA Polymerase alpha holoenzyme Associated Protein P1, DNA Polymerase alpha holoenzyme-Associated Protein P1, DNA replication Factor MCM3, DNA Replication Licensing Factor MCM3, HCC 5, HCC5, hRlf beta Subunit, Human cervical Cancer proto Oncogene 5, MCM 3, mcm3, MCM3 minichromos ... 224059
Acts as component of the MCM2-7 complex (MCM complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells.
The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit.
The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity.
Required for DNA replication and cell proliferation.
Applications:Suitable for use in Western Blot, Immunohistochemistry.
Other applications not tested.
Recommended Dilution:Western Blot: 1:500-1:2000Immunohistochemistry: 1:50-1:200Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size:50ul
Host:rabbit
Source Antibody:human
Grade:Affinity Purified
Purity:Purified by immunoaffinity chromatography.
Form:Supplied as a liquid PBS, 0.1% sodium azide, 50% glycerol.
Specificity:Recognizes endogenous levels of MCM3. Species Crossreactivity: Human, mouse, rat
Isotype:IgG
Calc Applications Abbrev:IHC WB
Calc Crossreactivity:Hu Mo Rt
Immunogen:Recombinant full length Human MCM3.
Shelf Life:1year
Swiss Prot Number:P25205
EU Commodity Code:30021010
商品名:MCM3 (Cervical Cancer proto Oncogene 5, DNA Polymerase alpha holoenzyme Associated P1, DNA Polymerase alpha holoenzyme Associated Protein P1, DNA Polymerase alpha holoenzyme-Associated Protein P1, DNA replication Factor MCM3, DNA Replication Licensing Factor MCM3, HCC 5, HCC5, hRlf beta Subunit, Human cervical Cancer proto Oncogene 5, MCM 3, mcm3, MCM3 minichromosome maintenance deficient 3, MCM3, MGC1157, Minichromosome maintenance Complex Component 3, Minichromosome maintenance) 50ul