84-2360-91　［取扱停止］MC5-R (Melanocortin Receptor 5, MC5-R, MC-2, MC5R) 50ul　224049

特徴

• The melanocortin family comprises the alpha-, beta- and y-melanocyte stimulating hormones (MSH) and adrenocorticotrophin.
• The receptors for these hormones are seven-transmembrane, G protein-coupled proteins that activate adenylyl cyclase.
• Five melanocortin receptors have been cloned and shown to exhibit different affinities and patterns of expression.
• MC1-R (MSH-R) is expressed in melanocytes and corticoadrenal tissue.
• MC2-R is the ACTH receptor and is expressed primarily in the adrenal cortex.
• MC3-R has been found in specific regions of the brain and is also expressed in placenta and gut.
• MC4-R is expressed primarily in brain, while MC5-R is expressed at low levels in most tissues.
• Applications:Suitable for use in Immunofluorescence, Western Blot.
• Other applications not tested.
• Recommended Dilution:Western Blot: 1:500-1:1000Immunofluorescence: 1:50-1:200Optimal dilutions to be determined by the researcher.
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months after receipt.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.