Microtubules, the primary component of the cytoskeletal network, interact with proteins called microtubule-associated proteins (MAPs).
The microtubule-associated proteins can be divided into two groups, structural and dynamic.
The MAP proteins function to stimulate tubulin assembly, enhance microtubule stability, influence the spatial distribution of microtubules within cells and utilize microtubule polarity to translocate cellular components.
MAP-4 is a non-neuronal microtubule-associated protein that contains three, 18 amino acid repeats that are homologous to the repeats found in several other MAP proteins.
Studies have shown that MAP-4 is involved with interphase microtubule, mitotic spindle fibers and mitotic movements.
The protein, which promotes microtubule assembly, is primarily expressed in kidney, lung, liver, testis and spleen.
Applications:Suitable for use in Western Blot, Immunohistochemistry.
Other applications not tested.
Recommended Dilution:Western Blot: 1:500-1:2000Immunohistochemistry: 1:50-1:200Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size:100ul
Host:rabbit
Source Antibody:human
Grade:Affinity Purified
Purity:Purified by immunoaffinity chromatography.
Form:Supplied as a liquid PBS, 0.1% sodium azide, 50% glycerol.
Specificity:Recognizes endogenous levels of MAP4. Species Crossreactivity: Human