84-2360-06　［取扱停止］MAOA (Amine Oxidase [flavin-Containing] A, Monoamine Oxidase Type A, MAO-A, MAOA) 100ul　224004

特徴

• Monoamine oxidase (MAO) is an enzyme of the mitochondrial outer membrane and catalyzes the oxidative deamination of biogenic amines throughout the body.
• MAO is critical in the neuronal metabolism of catecholamine and indolamine transmitters.
• Cultured skin fibroblasts show both MAO-A and MAO-B and both MAOs differ in molecular structur.
• MAO-A, the primary type in fibroblasts, preferentially degrades serotonin and norepinephrine.
• Only MAO-B is present in platelets and only MAO-A is present in trophoblasts.
• MAO-B, the primary type found not only in platelets but also in the brain of man and other primates, preferentially degrades phenylethylamine and benzylamine.
• MAO has been of particular interest to psychiatry and genetics because of the suggestion that low activity is a ‘genetic marker’ for schizophrenia.
• Applications:Suitable for use in Western Blot, Immunohistochemistry.
• Other applications not tested.
• Recommended Dilution:Western Blot: 1:500-1:2000Immunohistochemistry: 1:50-1:200Optimal dilutions to be determined by the researcher.
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months after receipt.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.