LZTR1, leucine-zipper-like transcriptional regulator 1, is a member of the BTBkelch superfamily.
LZTR1 contains 2 BTB (POZ) domains and 6 Kelch repeats.
The BTB (broad-Complex, Tramtrack and Bric a brac) domain, also known as the POZ (POxvirus and Zinc finger) domain, is an N-terminal homodimerization domain that contains multiple copies of kelch repeats and/or C2 H2-type zinc fingers.
Proteins that contain BTB domains are thought to be involved in transcriptional regulation via control of chromatin structure and function.
LZTR1 is believed to function as a transcriptional regulator during embryogenesis.
LZTR1 is expressed in fetal brain, heart, kidney, liver and lung and is found exclusively on the cytoplasmic surface of the Golgi network.
LZTR1 likely contributes to the etiology of velocardiofacial/DiGeorge syndrome, as the LZTR1 gene lies within a chromosomal deletion region associated with the disease.
Applications:Suitable for use in Western Blot.
Other applications not tested.
Recommended Dilution:Western Blot: 1:500-1:1000Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：100ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid PBS, 0.05% sodium azide, pH 7.2.
Specificity：Recognizes endogenous levels of LZTR1. Species Crossreactivity: Human, mouse, rat
Isotype：IgG
Calc Applications Abbrev：WB
Calc Crossreactivity：Hu Mo Rt
Immunogen：A synthetic peptide corresponding to residues in Human LZTR1.
