84-2359-27　［取扱停止］LY86 (BPAD, dJ80N2.1, Ly 86, Ly-86, LY86, LY86_HUMAN, Lymphocyte Antigen 86, Lymphocyte Antigen 86 Precursor, Major affective disorder 1, MD 1, MD1 Protein, MD1 RP105 Associated, MD1 RP105 Associated, MMD 1, Protein MD 1, Protein MD-1, RP1-80N2.1,) 100ul　223965

特徴

• RP105 (CD180) was originally discovered as a mouse B cell surface molecule that transmits an activation signal.
• This signal leads to resistance against irradiation-induced apoptosis and massive B cell proliferation.
• RP105 is associated with another molecule, MD-1, which has an important role in the cell surface expression of RP105.
• MD-1, also known as lymphocyte antigen 68 and RP105 associated protein, associates with and regulates the cell surface expression of RP105.
• RP105/MD-1 constitutes an LPS-signaling complex on B cells and, like MD-2, enhances the LPS signaling via TLR4.
• MD-1 contains 162 amino acids and has a predicted 19 amino acid signal peptide and 2 N-glycosylation sites.
• MD-1 is highly expressed in B cells, monocytes and tonsil, and is localized on the surface of cells despite its lack of a transmembrane region.
• Applications:Suitable for use in Western Blot and Immunohistochemistry.
• Other applications not tested.
• Recommended Dilution:Western Blot: 1:500-1:2000Immunohistochemistry: 1:50-1:200Optimal dilutions to be determined by the researcher.
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months after receipt.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.