The Lim class homeobox gene Lmx1b is required for the normal development of the dopaminergic system.
Loss of dopaminergic neurons is associated with one of the most prominent human neurological disorders, Parkinson's disease (PD).
Dopaminergic neurons play an important role in the control of multiple brain functions including voluntary movement alongside an array of behavioral processes such as mood, reward, addiction, and stress.
Lmx1b is one of several transcription factors involved in the generation of dopaminergic neurons in the brain.
Applications:Suitable for use in Western Blot, Immunohistochemistry.
Other applications not tested.
Recommended Dilution:Western Blot: 1:500-1:1000Immunohistochemistry: 1:50-1:200Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：50ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid PBS, 15mM sodium azide, pH 7.2.
Specificity：Recognizes endogenous levels of LMX1B. Species Crossreactivity: Human, mouse, rat
Isotype：IgG
Calc Applications Abbrev：IHC WB
Calc Crossreactivity：Hu Mo Rt
Immunogen：Synthetic peptide corresponding to amino acids 131-180 of Human LMX1B.
