84-2357-83　［取扱停止］LDHA (Cell Proliferation-inducing Gene 19 Protein, GSD11, L lactate Dehydrogenase A Chain, L-lactate Dehydrogenase A Chain, l7R2, Lactate Dehydrogenase 1, A Chain, Lactate Dehydrogenase A, Lactate Dehydrogenase A4, Lactate Dehydrogenase M, LDH A, LDH M, LDH muscle Subunit, LDH muscle Subunit, M LDH, LDH-A, LDH-M, LDH1, ldha, LDHA, LDHM, OTTMUSP00000017774, PIG19, ...　223892

特徴

• The lactate dehydrogenase family (LDH) catalyzes the final step of anaerobic glycolysis, the conversion of L-lactate and NAD to pyruvate and NADH.
• The LDH family consists of three members, LDH-A, LDH-B, and LDH-C, all of which form tetramers consisting four subunits.
• However, each family member displays a specific tissue distribution pattern with LDH-A and LDH-B predominant in several tissues, specifically LDH-A in muscle and LDH-B in heart, while LDH-C expression is confined to the testis and sperm.
• LDHs function as powerful markers for germ cell tumors.
• The genes encoding human LDH-A and LDH-C map to chromosome 11, while the human LDH-B gene maps to chromosome 12.
• Deficiency in the LDH-A gene is linked to exertional myoglobinuria.
• Applications:Suitable for use in Western Blot, Immunohistochemistry and Immunoprecipitation.
• Other applications not tested.
• Recommended Dilution:Western Blot: 1:500-1:2000Immunohistochemistry: 1:50-1:200Immunoprecipitation: 1:50-1:100Optimal dilutions to be determined by the researcher.
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months after receipt.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.