The human voltage-gated potassium (KV) channel KV3.1 gene maps to chromosome 11p15 and encodes a protein that resembles Drosophila Shaw subfamily channel types.
KV channels are multimers that contain channel activity-dependent alpha subunits and modulatory gamma subunits.
Neuronal populations in the CNS coexpressing KV3.1 and KV3.3 influence fast repolarization of action potentials and enable neurons to fire repetitively at high frequencies.
KV3 genes produce multiple splice variants in the 3' ends of respective transcript, which may influence normal spatial ion permeability of excitable membranes in the brain.
Applications:Suitable for use in Western Blot.
Other applications not tested.
Recommended Dilution:Western Blot: 1:500-1:1000Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：50ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid PBS, 0.05% sodium azide, pH 7.2.
Specificity：Recognizes endogenous levels of Kv3.1. Species Crossreactivity: Human, mouse, rat
Isotype：IgG
Calc Applications Abbrev：WB
Calc Crossreactivity：Hu Mo Rt
Immunogen：Synthetic peptide corresponding to amino acids 254-299 of Human Kv3.1.
