84-2356-71 ［取扱停止］Ku-70 (X-Ray Repair Cross-Complementing Protein 6, 5'-deoxyribose-5-phosphate Lyase Ku70, 5'-dRP Lyase Ku70, 70kD Subunit of Ku Antigen, ATP-Dependent DNA Helicase 2 Subunit 1, ATP-Dependent DNA Helicase II 70kD Subunit, CTC box-Binding Factor 75kD Subunit, CTC75, CTCBF, DNA Repair Protein XRCC6, Lupus Ku Autoantigen Protein p70, Ku70, Thyroid-lupus Autoantigen, T ... 223835
84-2356-71 ［取扱停止］Ku-70 (X-Ray Repair Cross-Complementing Protein 6, 5'-deoxyribose-5-phosphate Lyase Ku70, 5'-dRP Lyase Ku70, 70kD Subunit of Ku Antigen, ATP-Dependent DNA Helicase 2 Subunit 1, ATP-Dependent DNA Helicase II 70kD Subunit, CTC box-Binding Factor 75kD Subunit, CTC75, CTCBF, DNA Repair Protein XRCC6, Lupus Ku Autoantigen Protein p70, Ku70, Thyroid-lupus Autoantigen, T ... 223835
The Ku protein is localized in the nucleus and is composed of subunits referred to as Ku-70 (or p70) and Ku-86 (or p86), which is also known by the synonym Ku-80 (or p80).
Ku was first described as an autoantigen to which antibodies were produced in a patient with scleroderma-polymyositis overlap syndrome, and was later found in the sera of patients with other rheumatic diseases.
Both subunits of the Ku protein have been cloned, and a number of functions have been proposed for Ku, including cell signaling, DNA replication and transcriptional activation.
Applications:Suitable for use in Immunofluorescence, Western Blot, Immunohistochemistry.
Other applications not tested.
Recommended Dilution:Western Blot: 1:500-1:1000Immunohistochemistry: 1:50-1:200Immunofluorescence: 1:50-1:200Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：50ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid PBS, 15mM sodium azide, pH 7.2.
Specificity：Recognizes endogenous levels of Ku-70. Species Crossreactivity: Human, mouse, rat
Isotype：IgG
Calc Applications Abbrev：IF IHC WB
Calc Crossreactivity：Hu Mo Rt
Immunogen：Synthetic peptide corresponding to amino acids 560-600 of Human Ku-70.
Shelf Life：1year
Swiss Prot Number：P12956
EU Commodity Code：30021010
商品名：Ku-70 (X-Ray Repair Cross-Complementing Protein 6, 5'-deoxyribose-5-phosphate Lyase Ku70, 5'-dRP Lyase Ku70, 70kD Subunit of Ku Antigen, ATP-Dependent DNA Helicase 2 Subunit 1, ATP-Dependent DNA Helicase II 70kD Subunit, CTC box-Binding Factor 75kD Subunit, CTC75, CTCBF, DNA Repair Protein XRCC6, Lupus Ku Autoantigen Protein p70, Ku70, Thyroid-lupus Autoantigen, TLAA, X-Ray Repair Complementing defective Repair in, Chinese hamster Cells 6, XRCC6, G22P1) 50ul
