The kinesin family of motor proteins comprise at least two forms of conventional kinesin, which are encoded by different genes and designated as ubiquitous kinesin, which is expressed in all cells and tissues, and neuronal kinesin, which is expressed exclusively in neuronal cells .
The motor protein kinesin is a heterotetramer composed of two heavy chains and two light chains.
While the kinesin heavy chain contains the motor activity, evidence suggests that the kinesin light chain is involved in either modulation of kinesin heavy chain activity or in cargo binding.
Kinesin-driven vesicle motility is dependent upon kinectin 1, a kinesin-binding protein .
Kinectin 1, also known as kinesin receptor, is an integral membrane protein in the ER .
Despite the kinesin-kinectin 1 interaction, a great deal of debate surrounds the involvement of kinectin 1 in microtubule-dependent transport .
Applications:Suitable for use in Western Blot, Immunohistochemistry.
Other applications not tested.
Recommended Dilution:Western Blot: 1:500-1:2000Immunohistochemistry: 1:50-1:200Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：50ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid PBS, 0.1% sodium azide, 50% glycerol.
Specificity：Recognizes endogenous levels of KTN1. Species Crossreactivity: Human, mouse, rat
