84-2356-25　［取扱停止］KLK1 (Kallikrein-1, Kallikrein 1, Kidney/pancreas/salivary gland kallikrein, Tissue kallikrein, KLK1) 50ul　223811

特徴

• Kallikreins (KLKs) belong to the serine protease family of proteolytic enzymes.
• Human pancreatic/renal KLK encodes for the KLK1 enzyme, which is involved in post-translational processing of polypeptide precursors.
• The function of the other members of KLK gene family is currently unknown, but evidence suggests that many KLKs are implicated in carcinogenesis.
• The human KLK gene family consists of 15 serine proteases.
• The human KLK genes are clustered on chromosome 19q13.
• Unlike other kalllikreins, the KLK4-15 encoded proteases are less related and do not contain a conventional KLK loop.
• Clusters of genes exhibit high prostatic (KLK2-4, KLK15) or pancreatic (KLK6-13) expression.
• Applications:Suitable for use in Western Blot, Immunohistochemistry.
• Other applications not tested.
• Recommended Dilution:Western Blot: 1:500-1:2000Immunohistochemistry: 1:50-1:200Optimal dilutions to be determined by the researcher.
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months after receipt.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.