Krüppel-like factors (KLFs) comprise a family of evolutionarily conserved zinc finger-containing transcription factors with diverse regulatory functions in cell growth, proliferation, differentiation and embryogenesis.
Individual members of the Sp1-like/KLF family can function either as activators or repressors, depending on which promoter they bind and which coregulators they interact with.
KLF17 (Krüppel-like factor 17), whose alternative names include ZNF393 (zinc finger protein 393) or zfp393, is a 389 amino acid nuclear protein belonging to the Sp1 C2H2-type zinc-finger protein family.
Expressed in testis and ovary, KLF17 may function as a germ cell-specific transcription factor involved in oocyte development and spermatid differentiation.
Containing three C2H2-type zinc fingers which bind G/C-rich sites, KLF17 activates transcription from CACCC-box elements.
Applications:Suitable for use in Western Blot.
Other applications not tested.
Recommended Dilution:Western Blot: 1:500-1:1000Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：50ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid PBS, 0.05% sodium azide, pH 7.2.
Specificity：Recognizes endogenous levels of KLF17. Species Crossreactivity: Human, mouse, rat
Isotype：IgG
Calc Applications Abbrev：WB
Calc Crossreactivity：Hu Mo Rt
Immunogen：A synthetic peptide corresponding to residues in Human KLF17.
