The Kinesins constitute a large family of microtubule-dependent motor proteins which are responsible for the distribution of numerous organelles, vesicles and macromolecular complexes throughout the cell.
Individual Kinesin members play crucial roles in cell division, intracellular transport and membrane trafficking events, including endocytosis and transcytosis.
KIF20A (kinesin family member 20A), also known as Rabkinesin-6, RAB6KIFL (Rab6-interacting kinesin-like protein), GG10_2 or MKLP2 (mitotic kinesin-like protein 2), is a 890 amino acid protein that contains one kinesin-motor domain and belongs to the Kinesin-like protein family.
KIF20A locates to the Golgi apparatus and interacts with guanosine triphosphate (GTP)-bound forms of RAB 6.
KIF20A may be responsible for the retrograde RAB 6 regulated transport of Golgi membranes and related vesicles along microtubules.
Applications:Suitable for use in Western Blot.
Other applications not tested.
Recommended Dilution:Western Blot: 1:500-1:1000Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：100ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid PBS, 15mM sodium azide, pH 7.2.
Specificity：Recognizes endogenous levels of KIF20A. Species Crossreactivity: Human, mouse, rat
Isotype：IgG
Calc Applications Abbrev：WB
Calc Crossreactivity：Hu Mo Rt
Immunogen：Synthetic peptide corresponding to amino acids 501-550 of Human KIF20A.
