Ki-67 is a nuclear protein that is expressed in proliferating cells and may be required for maintaining cell proliferation.
Ki-67 has been used as a marker for cell proliferation of solid tumors and some hematological malignancies.
A correlation has been demonstrated between Ki-67 index and the histopathological grade of neoplasms.
Assessment of Ki-67 expression in renal and ureter tumors shows a correlation between tumor proliferation and disease progression, thus making it possible to differentiate high-risk patients.
Ki-67 expression may also prove to be important for distinguishing between malignant and benign peripheral nerve sheath tumors.
Applications:Suitable for use in Western Blot, Immunohistochemistry.
Other applications not tested.
Recommended Dilution:Western Blot: 1:500-1:2000Immunohistochemistry: 1:50-1:200Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：100ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid PBS, 0.1% sodium azide, 50% glycerol.
Specificity：Recognizes endogenous levels of Ki-67. Species Crossreactivity: Human
