84-2355-50　［取扱停止］KCNH2 (Potassium Voltage-Gated Channel Subfamily H Member 2, Eag Homolog, Ether-a-go-go-Related Gene Potassium Channel 1, ERG-1, Eag-Related Protein 1, Ether-a-go-go-Related Protein 1, H-ERG, hERG-1, hERG1, Voltage-Gated Potassium Channel Subunit Kv11.1, ERG, ERG1, HERG) 50ul　223771

特徴

• This gene encodes a voltage-activated potassium channel belonging to the eag family.
• It shares sequence similarity with the Drosophila ether-a-go-go (eag) gene.
• Mutations in this gene can cause long QT syndrome type 2 (LQT2).
• Transcript variants encoding distinct isoforms have been identified.
• Pore-forming (alpha) subunit of voltage-gated inwardly rectifying potassium channel.
• Channel properties are modulated by cAMP and subunit assembly.
• Mediates the rapidly activating component of the delayed rectifying potassium current in heart (IKr).
• Isoform 3 has no channel activity by itself, but modulates channel characteristics when associated with isoform 1.
• Applications:Suitable for use in Western Blot.
• Other applications not tested.
• Recommended Dilution:Western Blot: 1:500-1:2000Optimal dilutions to be determined by the researcher.
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months after receipt.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.