Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain.
This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form the integrin lymphocyte function-associated antigen-1 (LFA-1), which is expressed on all leukocytes.
LFA-1 plays a central role in leukocyte intercellular adhesion through interactions with its ligands, ICAMs 1-3 (intercellular adhesion molecules 1 through 3), and also functions in lymphocyte costimulatory signaling.
Two transcript variants encoding different isoforms have been found for this gene.
Applications:Suitable for use in Western Blot.
Other applications not tested.
Recommended Dilution:Western Blot: 1:500-1:2000Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：100ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid PBS, pH 7.2, 0.02% sodium azide, 50% glycerol.
Specificity：Recognizes endogenous levels of human ITGAL. Species Crossreactivity: mouse and rat
Isotype：IgG
Calc Applications Abbrev：WB
Calc Crossreactivity：Hu Mo Rt
Immunogen：Recombinant protein corresponding to full length human ITGAL.
Shelf Life：1year
Swiss Prot Number：P20701
EU Commodity Code：30021010
商品名：ITGAL (Antigen CD11A (p180), Lymphocyte function Associated Antigen 1, alpha Polypeptide, Antigen CD11A, CD 11a, CD11 Antigen-like Family Member A, CD11a, CD11a Antigen, Integrin Alpha L, Integrin alpha-L, Integrin Gene promoter, Integrin, alpha L (Antigen CD11A (p180), Lymphocyte function Associated Antigen 1, alpha Polypeptide), ITAL_HUMAN, ITGAL, ITGAL Protein, Leukocyte Adhesion Glycoprotein LFA 1 alpha Chain, Leukocyte Adhesion Glycoprotein LFA-1 alpha Chain, Leukocyte Adhesion Glycoprotein LFA1 Alpha Chain, Leukocyte function Associated Molecule 1 alpha Chain, Leukocyte function-Associated Molecule 1 alpha Chain, LFA 1 alpha, LFA 1, LFA 1A, LFA-1A, LFA1A, Ly15, Ly21, Lymphocyte function Associated Antigen 1, Lymphocyte Function Associated Antigen Type 1 alpha, p180) 100ul
