84-2352-59 [取扱停止]ING3 (Eaf 4, Eaf4, FLJ20089, ING 2, ING 3, ING2, Inhibitor of Growth Family Member 3, Inhibitor of Growth Protein 3, MEAF4, p47 ING 3, p47 ING3, p47 Regulator Protein, p47ING3, p47ING3 Protein) 50ul 223625
84-2352-59 [取扱停止]ING3 (Eaf 4, Eaf4, FLJ20089, ING 2, ING 3, ING2, Inhibitor of Growth Family Member 3, Inhibitor of Growth Protein 3, MEAF4, p47 ING 3, p47 ING3, p47 Regulator Protein, p47ING3, p47ING3 Protein) 50ul 223625
ING3 belongs to a family of proteins containing the plant homeodomain (PHD) finger, which includes transcription factors and proteins that regulate chromatin structure.
ING3 is a component of the NuA4 histone acetyltransferase (HAT) complex and can activate p53 trans-activated promoters, including promoters of p21/waf1 and bax.
Overexpression of ING3 has been shown to inhibit cell growth and induce apoptosis.
Allelic loss and reduced expression of the ING3 gene were detected in head and neck cancers.
Applications:Suitable for use in Western Blot, Immunohistochemistry.
Other applications not tested.
Recommended Dilution:Western Blot: 1:500-1:2000Immunohistochemistry: 1:50-1:200Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size:50ul
Host:rabbit
Source Antibody:human
Grade:Affinity Purified
Purity:Purified by immunoaffinity chromatography.
Form:Supplied as a liquid PBS, 0.1% sodium azide, 50% glycerol.
Specificity:Recognizes endogenous levels of ING3. Species Crossreactivity: Human, mouse, rat