Interleukin-9, or IL-9, is a TH2 cytokine that has been shown to promote the antigen-independent growth of some T helper clones.
IL-9 is a pleiotropic cytokine with multiple functions on cells of lymphoid, myeloid and mast cell lineages.
Both mouse and human cDNAs encode 144 amino acid precursors with 18 amino acid residue signal peptides that are cleaved to form the mature biologically active glycoprotein.
Although IL-9 is constitutively expressed in vitro by several transformed T cell lines, IL-9 expression can be induced in human peripheral blood T lymphocytes by T cell activators such as phorbol esters (PHA) and anti-CD3 antibodies.
IL-9 exerts its biological effects through the interleukin-9 receptor, IL-9R.
IL-9R is composed of at least two subunits: t
Applications:Suitable for use in Western Blot, Immunohistochemistry.
Other applications not tested.
Recommended Dilution:Western Blot: 1:500-1:2000Immunohistochemistry: 1:50-1:200Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：50ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid PBS, 0.1% sodium azide, 50% glycerol.
Specificity：Recognizes endogenous levels of IL9. Species Crossreactivity: Human
