84-2351-99　［取扱停止］IL22 (Cytokine Zcyto18, IL 10 Related T Cell derived inducible Factor, IL 21, IL 22, IL D110, IL TIF, IL-10-Related T-Cell-derived-inducible Factor, IL-22, IL-TIF, IL21, Il22, IL22_HUMAN, ILD110, ILTIF, Interleukin 10 Related T Cell derived inducible Factor, Interleukin 10-Related T Cell-derived inducible Factor, interleukin 21, Interleukin 22, Interleukin-22, MGC ...　223594

特徴

• IL-10-related T cell-derived inducible factor (IL-22, also known as IL-TIF) is a cytokine that was originally identified in mouse as an IL-9 inducible gene in T cells and mast cells and shows 22% amino acid identity with IL-10.
• Additionally, IL-22 is induced by IL-9 in thymic lymphomas and by lectins in freshly isolated splenocytes.
• IL-22 is found in both the thymus and brain, which suggests that the role of this factor is not restricted to the immune system.
• IL-22 is a ligand for CRF2-4, a member of the class II cytokine receptor family.
• In contrast to IL-10, IL-22 does not inhibit the production of proinflammatory cytokines by monocytes in response to lipopolysaccharide nor does it impact IL-10 function on monocytes, but it has modest inhibitory effects on IL-4 production from Th2 T cells.
• Applications:Suitable for use in Western Blot, Immunohistochemistry.
• Other applications not tested.
• Recommended Dilution:Western Blot: 1:500-1:2000Immunohistochemistry: 1:50-1:200Optimal dilutions to be determined by the researcher.
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months after receipt.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.