84-2351-89　［取扱停止］IL1R2 (IL1 Receptor II, Antigen CDw121b, CD121, CD121 Antigen-like Family Member B, CD121b, CD121B Antigen, CDw121b, IL-1R-2, IL-1R-beta, IL-1R2, IL-1RT-2, IL-1RT2, IL1 R2, IL1 Receptor beta Chain, IL1R beta, Il1r-2, IL1R2, IL1R2_HUMAN, IL1RB, Interleukin 1 Receptor Type II Precursor, Interleukin 1 Receptor, beta, Type II, Interleukin 1 Receptor, Type II, Interleu ...　223589

特徴

• The protein encoded by this gene is a cytokine receptor that belongs to the interleukin 1 receptor family.
• This protein binds interleukin alpha (IL1A), interleukin beta (IL1B), and interleukin 1 receptor, type I(IL1R1/IL1RA), and acts as a decoy receptor that inhibits the activity of its ligands.
• Interleukin 4 (IL4) is reported to antagonize the activity of interleukin 1 by inducing the expression and release of this cytokine.
• This gene and three other genes form a cytokine receptor gene cluster on chromosome 2q12.
• Alternative splicing results in multiple transcript variants and protein isoforms.
• Alternative splicing produces both membrane-bound and soluble proteins.
• A soluble protein is also produced by proteolytic cleavage.
• Applications:Suitable for use in Western Blot and Immunohistochemistry.
• Other applications not tested.
• Recommended Dilution:Western Blot: 1:500-1:2000Immunohistochemistry (paraffin): 1:50-1:200Optimal dilutions to be determined by the researcher.
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months after receipt.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.