84-2351-64　IL-8 (Interleukin-8, IL-8, C-X-C Motif Chemokine 8, Emoctakin, Granulocyte chemotactic Protein 1, GCP-1, Monocyte-derived neutrophil chemotactic Factor, MDNCF, Monocyte-derived neutrophil-Activating peptide, MONAP, Neutrophil-Activating Protein 1, NAP-1 Protein 3-10C, T-Cell chemotactic Factor, CXCL8, IL8) 50ul　223576

特徴

• IL-8 has been shown to function as a potent neutrophil chemostatic and activating peptide and is an important mediator of inflammatory diseases.
• Two distinct human IL-8 receptors, designated IL-8RA and IL-8RB, have been characterized.
• Both are expressed at a high level on neutrophils, and to a lesser extent on monocytes and myeloid cell lines.
• In addition, the IL-8RA subunit is expressed in T cells such as the Jurkat cell line.
• Both IL-8Rs are members of the seven-transmembrane domain rhodopsin superfamily of receptors and as such, couple G proteins for signal transduction.
• The two receptors share 77% amino acid identity.
• Applications:Suitable for use in Western Blot and Immunohistochemistry.
• Other applications not tested.
• Recommended Dilutions:Western Blot: 1:500-1:1000Immunohistochemistry (Paraffin: 1:50-1:200Optimal dilutions to be determined by the researcher.
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months after receipt.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.